| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Jesse Carlson | 67.2 | 1 | 6 | 4.66 | 0 | 3 | 51 | 21 | 0.258 |
| Jeremy Sowers | 123.1 | 6 | 11 | 5.25 | 0 | 0 | 51 | 52 | 0.281 |
| Brian Sanches | 56.1 | 4 | 2 | 2.56 | 0 | 3 | 51 | 26 | 0.235 |
| Kyle McClellan | 66.2 | 4 | 4 | 3.38 | 3 | 6 | 51 | 34 | 0.229 |
| Chris Young | 76.0 | 4 | 6 | 5.21 | 0 | 0 | 50 | 40 | 0.246 |
| Brett Myers | 70.2 | 4 | 3 | 4.84 | 0 | 0 | 50 | 23 | 0.272 |
| Rick VandenHurk | 58.2 | 3 | 2 | 4.30 | 0 | 0 | 49 | 21 | 0.252 |
| Matt Albers | 67.0 | 3 | 6 | 5.51 | 0 | 4 | 49 | 36 | 0.303 |
| Bobby Jenks | 53.1 | 3 | 4 | 3.71 | 29 | 35 | 49 | 16 | 0.250 |
| Jim Johnson | 70.0 | 4 | 6 | 4.11 | 10 | 16 | 49 | 23 | 0.270 |
| Phil Coke | 60.0 | 4 | 3 | 4.50 | 2 | 7 | 49 | 20 | 0.209 |
| Koji Uehara | 66.2 | 2 | 4 | 4.05 | 0 | 0 | 48 | 12 | 0.270 |
| Clayton Richard | 64.0 | 5 | 2 | 4.08 | 0 | 0 | 48 | 34 | 0.254 |
| Arthur Rhodes | 53.1 | 1 | 1 | 2.53 | 0 | 2 | 48 | 20 | 0.198 |
| Carlos Fisher | 52.1 | 1 | 1 | 4.47 | 0 | 1 | 48 | 31 | 0.262 |
| Kevin Jepsen | 54.2 | 6 | 4 | 4.94 | 1 | 2 | 48 | 19 | 0.292 |
| Mark DiFelice | 51.2 | 4 | 1 | 3.66 | 0 | 1 | 48 | 15 | 0.245 |
| Tony Sipp | 40.0 | 2 | 0 | 2.93 | 0 | 0 | 48 | 25 | 0.194 |
| Craig Stammen | 105.2 | 4 | 7 | 5.11 | 0 | 0 | 48 | 24 | 0.271 |
| Trevor Hoffman | 54.0 | 3 | 2 | 1.83 | 37 | 41 | 48 | 14 | 0.183 |
| Jesse Chavez | 67.1 | 1 | 4 | 4.01 | 0 | 4 | 47 | 22 | 0.264 |
| Garrett Olson | 80.1 | 3 | 5 | 5.60 | 0 | 0 | 47 | 34 | 0.258 |
| Wesley Wright | 44.2 | 3 | 4 | 5.44 | 0 | 2 | 47 | 25 | 0.299 |
| Chris Jakubauskas | 93.0 | 6 | 7 | 5.32 | 0 | 1 | 47 | 27 | 0.254 |
| Jose Arredondo | 45.0 | 2 | 3 | 6.00 | 0 | 1 | 47 | 23 | 0.269 |
| Matt Guerrier | 76.1 | 5 | 1 | 2.36 | 1 | 4 | 47 | 16 | 0.207 |
| Ángel Guzmán | 61.0 | 3 | 3 | 2.95 | 1 | 1 | 47 | 23 | 0.192 |
| Edinson Vólquez | 49.2 | 4 | 2 | 4.35 | 0 | 0 | 47 | 32 | 0.191 |
| Russ Springer | 41.2 | 0 | 1 | 4.10 | 0 | 1 | 47 | 14 | 0.299 |
| Trever Miller | 43.2 | 4 | 1 | 2.06 | 0 | 1 | 46 | 11 | 0.197 |
| Rich Hill | 57.2 | 3 | 3 | 7.80 | 0 | 0 | 46 | 40 | 0.296 |
| Bob Howry | 63.2 | 2 | 6 | 3.39 | 0 | 3 | 46 | 23 | 0.214 |
| Chris Narveson | 47.0 | 2 | 0 | 3.83 | 0 | 0 | 46 | 16 | 0.247 |
| Brian Fuentes | 55.0 | 1 | 5 | 3.93 | 48 | 55 | 46 | 24 | 0.254 |
| Mitchell Boggs | 58.0 | 2 | 3 | 4.19 | 0 | 0 | 46 | 33 | 0.311 |
| Matt Capps | 54.1 | 4 | 8 | 5.80 | 27 | 32 | 46 | 17 | 0.324 |
| Esmerling Vásquez | 53.0 | 3 | 3 | 4.42 | 0 | 4 | 45 | 29 | 0.255 |
| Dan Wheeler | 57.2 | 4 | 5 | 3.28 | 2 | 6 | 45 | 9 | 0.199 |
| Bruce Chen | 62.1 | 1 | 6 | 5.78 | 0 | 0 | 45 | 25 | 0.301 |
| Mike Adams | 37.0 | 0 | 0 | 0.73 | 0 | 1 | 45 | 8 | 0.111 |
| Jared Burton | 59.1 | 1 | 0 | 4.40 | 0 | 0 | 45 | 23 | 0.261 |
| Brian Stokes | 70.1 | 2 | 4 | 3.97 | 0 | 2 | 45 | 38 | 0.267 |
| Glen Perkins | 96.1 | 6 | 7 | 5.89 | 0 | 0 | 45 | 23 | 0.304 |
| LaTroy Hawkins | 63.1 | 1 | 4 | 2.13 | 11 | 15 | 45 | 16 | 0.253 |
| Chad Qualls | 52.0 | 2 | 2 | 3.63 | 24 | 29 | 45 | 7 | 0.256 |
| Manny Delcarmen | 59.2 | 5 | 2 | 4.53 | 0 | 3 | 44 | 34 | 0.270 |
| Ryan Franklin | 61.0 | 4 | 3 | 1.92 | 38 | 43 | 44 | 24 | 0.220 |
| Mitch Stetter | 45.0 | 4 | 1 | 3.60 | 1 | 2 | 44 | 27 | 0.216 |
| Daniel Ray Herrera | 61.2 | 4 | 4 | 3.06 | 0 | 0 | 44 | 24 | 0.276 |
| Jason Jennings | 61.0 | 2 | 4 | 4.13 | 1 | 2 | 44 | 28 | 0.286 |
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