| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Justin Verlander | 240.0 | 19 | 9 | 3.45 | 0 | 0 | 269 | 63 | 0.243 |
| Wade Davis | 36.1 | 2 | 2 | 3.72 | 0 | 0 | 36 | 13 | 0.243 |
| Francisco Cordero | 66.2 | 2 | 6 | 2.16 | 39 | 43 | 58 | 30 | 0.243 |
| Brian Bruney | 39.0 | 5 | 0 | 3.92 | 0 | 1 | 36 | 23 | 0.243 |
| Hiroki Kuroda | 117.1 | 8 | 7 | 3.76 | 0 | 0 | 87 | 24 | 0.243 |
| Jon Lester | 203.1 | 15 | 8 | 3.41 | 0 | 0 | 225 | 64 | 0.242 |
| Kevin Hart | 27.2 | 3 | 1 | 2.60 | 0 | 0 | 13 | 18 | 0.242 |
| Hideki Okajima | 61.0 | 6 | 0 | 3.39 | 0 | 2 | 53 | 21 | 0.242 |
| David Price | 128.1 | 10 | 7 | 4.42 | 0 | 0 | 102 | 54 | 0.241 |
| Sean Green | 69.2 | 1 | 4 | 4.52 | 1 | 3 | 54 | 36 | 0.240 |
| Matt Palmer | 121.1 | 11 | 2 | 3.93 | 0 | 0 | 69 | 55 | 0.240 |
| Matt Herges | 25.1 | 2 | 1 | 3.55 | 0 | 1 | 18 | 6 | 0.240 |
| Octavio Dotel | 62.1 | 3 | 3 | 3.32 | 0 | 3 | 75 | 36 | 0.239 |
| Brendan Donnelly | 25.1 | 3 | 0 | 1.78 | 2 | 2 | 25 | 9 | 0.239 |
| Ryan Rowland-Smith | 96.1 | 5 | 4 | 3.74 | 0 | 0 | 52 | 27 | 0.239 |
| Kip Wells | 26.1 | 0 | 2 | 6.49 | 2 | 2 | 18 | 18 | 0.237 |
| Jair Jurrjens | 215.0 | 14 | 10 | 2.60 | 0 | 0 | 152 | 75 | 0.237 |
| Josh Johnson | 209.0 | 15 | 5 | 3.23 | 0 | 0 | 191 | 58 | 0.237 |
| Leo Rosales | 45.1 | 2 | 1 | 4.76 | 0 | 0 | 31 | 12 | 0.237 |
| Renyel Pinto | 61.1 | 4 | 1 | 3.23 | 0 | 4 | 58 | 45 | 0.237 |
| Darren Oliver | 73.0 | 5 | 1 | 2.71 | 0 | 1 | 65 | 22 | 0.237 |
| Justin Miller | 56.2 | 3 | 3 | 3.18 | 0 | 0 | 36 | 27 | 0.236 |
| Steven Jackson | 43.0 | 2 | 3 | 3.14 | 0 | 1 | 21 | 22 | 0.236 |
| Joe Smith | 34.0 | 0 | 0 | 3.44 | 0 | 1 | 30 | 13 | 0.236 |
| Clay Zavada | 51.0 | 3 | 3 | 3.35 | 0 | 0 | 52 | 24 | 0.236 |
| Brian Sanches | 56.1 | 4 | 2 | 2.56 | 0 | 3 | 51 | 26 | 0.235 |
| Ken Takahashi | 27.1 | 0 | 1 | 2.96 | 0 | 0 | 23 | 14 | 0.235 |
| José Veras | 25.2 | 3 | 1 | 5.96 | 0 | 0 | 18 | 14 | 0.235 |
| Grant Balfour | 67.1 | 5 | 4 | 4.81 | 4 | 9 | 69 | 33 | 0.235 |
| C.J. Wilson | 73.2 | 5 | 6 | 2.81 | 14 | 18 | 84 | 32 | 0.234 |
| Rich Harden | 141.0 | 9 | 9 | 4.09 | 0 | 0 | 171 | 67 | 0.234 |
| Dennys Reyes | 41.0 | 0 | 2 | 3.29 | 1 | 1 | 33 | 21 | 0.233 |
| Clay Condrey | 42.0 | 6 | 2 | 3.00 | 1 | 2 | 25 | 14 | 0.233 |
| Matt Garza | 203.0 | 8 | 12 | 3.95 | 0 | 0 | 189 | 79 | 0.233 |
| Kerry Wood | 55.0 | 3 | 3 | 4.25 | 20 | 26 | 63 | 28 | 0.233 |
| Jeff Fulchino | 82.0 | 6 | 4 | 3.40 | 0 | 3 | 71 | 27 | 0.233 |
| Ramón Ramírez | 69.2 | 7 | 4 | 2.84 | 0 | 4 | 52 | 32 | 0.233 |
| Sergio Romo | 34.0 | 5 | 2 | 3.97 | 2 | 2 | 41 | 11 | 0.233 |
| CC Sabathia | 230.0 | 19 | 8 | 3.37 | 0 | 0 | 197 | 67 | 0.232 |
| Mark Lowe | 80.0 | 2 | 7 | 3.26 | 3 | 13 | 69 | 29 | 0.232 |
| Matt Cain | 217.2 | 14 | 8 | 2.89 | 0 | 0 | 171 | 73 | 0.232 |
| Chris Smith | 46.0 | 0 | 0 | 4.11 | 0 | 1 | 35 | 19 | 0.232 |
| Mat Latos | 50.2 | 4 | 5 | 4.62 | 0 | 0 | 39 | 23 | 0.232 |
| Pedro Feliciano | 59.1 | 6 | 4 | 3.03 | 0 | 2 | 59 | 18 | 0.231 |
| Matt Daley | 51.0 | 1 | 1 | 4.24 | 0 | 3 | 55 | 18 | 0.231 |
| Ted Lilly | 177.0 | 12 | 9 | 3.10 | 0 | 0 | 151 | 36 | 0.230 |
| Zack Greinke | 229.1 | 16 | 8 | 2.16 | 0 | 0 | 242 | 51 | 0.230 |
| Brett Tomko | 36.2 | 4 | 1 | 2.95 | 0 | 0 | 22 | 6 | 0.230 |
| Leo Núñez | 68.2 | 4 | 6 | 4.06 | 26 | 33 | 60 | 27 | 0.230 |
| Tyler Walker | 35.1 | 2 | 1 | 3.06 | 0 | 0 | 27 | 9 | 0.230 |
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