| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Rick VandenHurk | 58.2 | 3 | 2 | 4.30 | 0 | 0 | 49 | 21 | 0.252 |
| Chad Gaudin | 42.0 | 2 | 0 | 3.43 | 0 | 0 | 34 | 20 | 0.252 |
| Ryan Madson | 77.1 | 5 | 5 | 3.26 | 10 | 16 | 78 | 22 | 0.251 |
| Scott Downs | 46.2 | 1 | 3 | 3.09 | 9 | 13 | 43 | 13 | 0.251 |
| Scott Feldman | 189.2 | 17 | 8 | 4.08 | 0 | 0 | 113 | 65 | 0.250 |
| Julián Tavárez | 35.0 | 3 | 7 | 4.89 | 1 | 2 | 32 | 27 | 0.250 |
| Barry Zito | 192.0 | 10 | 13 | 4.03 | 0 | 0 | 154 | 81 | 0.250 |
| Wandy Rodríguez | 205.2 | 14 | 12 | 3.02 | 0 | 0 | 193 | 63 | 0.250 |
| Jesse Crain | 51.2 | 7 | 4 | 4.70 | 0 | 0 | 43 | 27 | 0.250 |
| Franklin Morales | 40.0 | 3 | 2 | 4.50 | 7 | 8 | 41 | 23 | 0.250 |
| Juan Gutiérrez | 71.0 | 4 | 3 | 4.06 | 9 | 10 | 66 | 30 | 0.250 |
| Bobby Jenks | 53.1 | 3 | 4 | 3.71 | 29 | 35 | 49 | 16 | 0.250 |
| Dennis Sarfate | 23.0 | 0 | 1 | 5.09 | 0 | 0 | 20 | 14 | 0.250 |
| Fernando Rodney | 75.2 | 2 | 5 | 4.40 | 37 | 38 | 61 | 41 | 0.249 |
| Jorge De La Rosa | 185.0 | 16 | 9 | 4.38 | 0 | 0 | 193 | 83 | 0.249 |
| Lance Cormier | 77.1 | 3 | 3 | 3.26 | 2 | 2 | 36 | 25 | 0.249 |
| Jensen Lewis | 66.1 | 2 | 4 | 4.61 | 1 | 5 | 62 | 29 | 0.249 |
| Eric O'Flaherty | 56.1 | 2 | 1 | 3.04 | 0 | 2 | 39 | 18 | 0.248 |
| Brandon Morrow | 69.2 | 2 | 4 | 4.39 | 6 | 8 | 63 | 44 | 0.248 |
| John Smoltz | 38.0 | 1 | 3 | 4.26 | 0 | 0 | 40 | 9 | 0.248 |
| Brandon Medders | 68.2 | 5 | 1 | 3.01 | 1 | 4 | 58 | 32 | 0.248 |
| Edwin Jackson | 214.0 | 13 | 9 | 3.62 | 0 | 0 | 161 | 70 | 0.247 |
| Scott Baker | 200.0 | 15 | 9 | 4.37 | 0 | 0 | 162 | 48 | 0.247 |
| A.J. Burnett | 207.0 | 13 | 9 | 4.04 | 0 | 0 | 195 | 97 | 0.247 |
| Chris Narveson | 47.0 | 2 | 0 | 3.83 | 0 | 0 | 46 | 16 | 0.247 |
| Brett Tomko | 20.2 | 1 | 2 | 5.23 | 0 | 0 | 11 | 7 | 0.247 |
| Ian Snell | 64.1 | 5 | 2 | 4.20 | 0 | 0 | 37 | 39 | 0.247 |
| Jamey Wright | 79.0 | 3 | 5 | 4.33 | 0 | 3 | 60 | 44 | 0.247 |
| Mike MacDougal | 50.0 | 1 | 1 | 3.60 | 20 | 21 | 31 | 31 | 0.247 |
| Todd Coffey | 83.2 | 4 | 4 | 2.90 | 2 | 6 | 65 | 21 | 0.247 |
| Luis Perdomo | 60.0 | 1 | 0 | 4.80 | 0 | 1 | 55 | 34 | 0.246 |
| Ryan Perry | 61.2 | 0 | 1 | 3.79 | 0 | 3 | 60 | 38 | 0.246 |
| Chris Young | 76.0 | 4 | 6 | 5.21 | 0 | 0 | 50 | 40 | 0.246 |
| John Grabow | 47.1 | 3 | 0 | 3.42 | 0 | 2 | 41 | 28 | 0.246 |
| Carlos Zambrano | 169.1 | 9 | 7 | 3.77 | 0 | 0 | 152 | 78 | 0.246 |
| Jered Weaver | 211.0 | 16 | 8 | 3.75 | 0 | 0 | 174 | 66 | 0.246 |
| Juan Cruz | 50.1 | 3 | 4 | 5.72 | 2 | 6 | 38 | 29 | 0.246 |
| Mark DiFelice | 51.2 | 4 | 1 | 3.66 | 0 | 1 | 48 | 15 | 0.245 |
| Shawn Camp | 79.2 | 2 | 6 | 3.50 | 1 | 1 | 58 | 29 | 0.245 |
| Peter Moylan | 73.0 | 6 | 2 | 2.84 | 0 | 5 | 61 | 35 | 0.245 |
| John Danks | 200.1 | 13 | 11 | 3.77 | 0 | 0 | 149 | 73 | 0.245 |
| Dustin Nippert | 69.2 | 5 | 3 | 3.88 | 0 | 0 | 54 | 29 | 0.245 |
| Johan Santana | 166.2 | 13 | 9 | 3.13 | 0 | 0 | 146 | 46 | 0.244 |
| Gavin Floyd | 193.0 | 11 | 11 | 4.06 | 0 | 0 | 163 | 59 | 0.244 |
| J.A. Happ | 166.0 | 12 | 4 | 2.93 | 0 | 0 | 119 | 56 | 0.244 |
| Takashi Saito | 55.2 | 3 | 3 | 2.43 | 2 | 4 | 52 | 25 | 0.244 |
| Adam Wainwright | 233.0 | 19 | 8 | 2.63 | 0 | 0 | 212 | 66 | 0.244 |
| Josh Beckett | 212.1 | 17 | 6 | 3.86 | 0 | 0 | 199 | 55 | 0.244 |
| Chad Billingsley | 196.1 | 12 | 11 | 4.03 | 0 | 0 | 179 | 86 | 0.244 |
| Doug Mathis | 42.2 | 0 | 1 | 3.16 | 1 | 1 | 25 | 10 | 0.244 |
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