| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Jeff Weaver | 79.0 | 6 | 4 | 3.65 | 0 | 0 | 64 | 33 | 0.281 |
| Matt Maloney | 40.2 | 2 | 4 | 4.87 | 0 | 0 | 28 | 8 | 0.281 |
| Matt Belisle | 31.0 | 3 | 1 | 5.52 | 0 | 0 | 22 | 5 | 0.280 |
| Mark Hendrickson | 105.0 | 6 | 5 | 4.37 | 1 | 3 | 61 | 33 | 0.280 |
| Bartolo Colón | 62.1 | 3 | 6 | 4.19 | 0 | 0 | 38 | 21 | 0.280 |
| Sean West | 103.1 | 8 | 6 | 4.79 | 0 | 0 | 70 | 44 | 0.280 |
| Jeff Karstens | 108.0 | 4 | 6 | 5.42 | 0 | 0 | 52 | 45 | 0.279 |
| Francisco Liriano | 136.2 | 5 | 13 | 5.80 | 0 | 0 | 122 | 65 | 0.279 |
| David Patton | 27.2 | 3 | 1 | 6.83 | 0 | 0 | 23 | 19 | 0.279 |
| Jamie Moyer | 162.0 | 12 | 10 | 4.94 | 0 | 0 | 94 | 43 | 0.279 |
| J.D. Martin | 77.0 | 5 | 4 | 4.44 | 0 | 0 | 37 | 24 | 0.279 |
| Joe Saunders | 186.0 | 16 | 7 | 4.60 | 0 | 0 | 101 | 64 | 0.279 |
| Chris Volstad | 159.0 | 9 | 13 | 5.21 | 0 | 0 | 107 | 59 | 0.278 |
| Pat Misch | 59.0 | 3 | 4 | 4.12 | 0 | 1 | 23 | 19 | 0.278 |
| Joel Peralta | 24.2 | 0 | 3 | 6.20 | 0 | 1 | 22 | 12 | 0.278 |
| Cliff Lee | 152.0 | 7 | 9 | 3.14 | 0 | 0 | 107 | 33 | 0.278 |
| Jason Bergmann | 48.0 | 2 | 4 | 4.50 | 0 | 1 | 40 | 25 | 0.278 |
| Tomo Ohka | 71.0 | 1 | 5 | 5.96 | 0 | 0 | 31 | 19 | 0.278 |
| Jeff Gray | 26.1 | 0 | 1 | 3.76 | 0 | 0 | 19 | 4 | 0.278 |
| Brian Shouse | 28.0 | 1 | 1 | 4.50 | 0 | 1 | 17 | 7 | 0.277 |
| Justin Speier | 40.0 | 4 | 2 | 5.18 | 0 | 1 | 39 | 15 | 0.277 |
| Clayton Richard | 89.0 | 4 | 3 | 4.65 | 0 | 0 | 66 | 37 | 0.276 |
| Daniel Ray Herrera | 61.2 | 4 | 4 | 3.06 | 0 | 0 | 44 | 24 | 0.276 |
| Jonathon Niese | 25.2 | 1 | 1 | 4.21 | 0 | 0 | 18 | 9 | 0.276 |
| Charlie Morton | 97.0 | 5 | 9 | 4.55 | 0 | 0 | 62 | 40 | 0.276 |
| Yusmeiro Petit | 89.2 | 3 | 10 | 5.82 | 0 | 0 | 74 | 34 | 0.276 |
| James Shields | 219.2 | 11 | 12 | 4.14 | 0 | 0 | 167 | 52 | 0.275 |
| Luke French | 29.1 | 1 | 2 | 3.38 | 0 | 0 | 19 | 11 | 0.275 |
| Mark Buehrle | 213.1 | 13 | 10 | 3.84 | 0 | 0 | 105 | 45 | 0.275 |
| Sean Marshall | 85.1 | 3 | 7 | 4.32 | 0 | 0 | 68 | 32 | 0.274 |
| Joel Zumaya | 31.0 | 3 | 3 | 4.94 | 1 | 7 | 30 | 22 | 0.274 |
| Antonio Bastardo | 23.2 | 2 | 3 | 6.46 | 0 | 0 | 19 | 9 | 0.274 |
| Anthony Reyes | 38.1 | 1 | 1 | 6.57 | 0 | 0 | 22 | 23 | 0.274 |
| Joba Chamberlain | 157.1 | 9 | 6 | 4.75 | 0 | 0 | 133 | 76 | 0.274 |
| Dirk Hayhurst | 22.2 | 0 | 0 | 2.78 | 0 | 0 | 13 | 9 | 0.274 |
| Andrew Miller | 80.0 | 3 | 5 | 4.84 | 0 | 0 | 59 | 43 | 0.273 |
| Blaine Boyer | 37.0 | 0 | 1 | 2.68 | 0 | 0 | 18 | 12 | 0.273 |
| Oliver Pérez | 66.0 | 3 | 4 | 6.82 | 0 | 0 | 62 | 58 | 0.273 |
| Edward Mujica | 93.2 | 3 | 5 | 3.94 | 2 | 3 | 76 | 19 | 0.273 |
| Brad Thompson | 80.0 | 2 | 6 | 4.84 | 0 | 0 | 34 | 23 | 0.273 |
| Pedro Martinez | 44.2 | 5 | 1 | 3.63 | 0 | 0 | 37 | 8 | 0.273 |
| Cole Hamels | 193.2 | 10 | 11 | 4.32 | 0 | 0 | 168 | 43 | 0.273 |
| Kyle Kendrick | 26.1 | 3 | 1 | 3.42 | 0 | 0 | 15 | 9 | 0.273 |
| Scott Kazmir | 111.0 | 8 | 7 | 5.92 | 0 | 0 | 91 | 50 | 0.273 |
| Tony Peña | 36.0 | 1 | 2 | 3.75 | 1 | 2 | 29 | 9 | 0.272 |
| Alberto Arias | 45.2 | 2 | 1 | 3.35 | 0 | 2 | 39 | 19 | 0.272 |
| Tim Wood | 22.1 | 1 | 0 | 2.82 | 0 | 0 | 16 | 10 | 0.272 |
| Micah Owings | 119.2 | 7 | 12 | 5.34 | 1 | 1 | 68 | 64 | 0.272 |
| Brett Myers | 70.2 | 4 | 3 | 4.84 | 0 | 0 | 50 | 23 | 0.272 |
| Bud Norris | 55.2 | 6 | 3 | 4.53 | 0 | 0 | 54 | 25 | 0.272 |
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