| MLB Pitching Statistics | |||||||||
| Player | IP | W | L | ERA | SV | SVO | K | BB | BAVG |
| Wade LeBlanc | 46.1 | 3 | 1 | 3.69 | 0 | 0 | 30 | 19 | 0.210 |
| Blake Hawksworth | 40.0 | 4 | 0 | 2.03 | 0 | 0 | 20 | 15 | 0.209 |
| Evan Meek | 47.0 | 1 | 1 | 3.45 | 0 | 1 | 42 | 29 | 0.209 |
| Jason Frasor | 57.2 | 7 | 3 | 2.50 | 11 | 14 | 56 | 16 | 0.209 |
| John Grabow | 25.0 | 0 | 0 | 3.24 | 0 | 0 | 16 | 12 | 0.209 |
| Mike González | 74.1 | 5 | 4 | 2.42 | 10 | 17 | 90 | 33 | 0.209 |
| Phil Coke | 60.0 | 4 | 3 | 4.50 | 2 | 7 | 49 | 20 | 0.209 |
| Matt Guerrier | 76.1 | 5 | 1 | 2.36 | 1 | 4 | 47 | 16 | 0.207 |
| Jason Bulger | 65.2 | 6 | 1 | 3.56 | 1 | 4 | 68 | 30 | 0.207 |
| José Valverde | 54.0 | 4 | 2 | 2.33 | 25 | 29 | 56 | 21 | 0.207 |
| Scott Eyre | 30.0 | 2 | 1 | 1.50 | 0 | 0 | 22 | 16 | 0.206 |
| Tim Lincecum | 225.1 | 15 | 7 | 2.48 | 0 | 0 | 261 | 68 | 0.206 |
| Brad Penny | 41.2 | 4 | 1 | 2.59 | 0 | 0 | 20 | 9 | 0.205 |
| Brandon Lyon | 78.2 | 6 | 5 | 2.86 | 3 | 6 | 57 | 31 | 0.205 |
| Chris Pérez | 33.1 | 0 | 1 | 4.32 | 1 | 3 | 38 | 12 | 0.205 |
| Joel Hanrahan | 31.1 | 0 | 1 | 1.72 | 0 | 0 | 37 | 20 | 0.204 |
| Nick Masset | 76.0 | 5 | 1 | 2.37 | 0 | 2 | 70 | 24 | 0.203 |
| Francisco Rodríguez | 68.0 | 3 | 6 | 3.71 | 35 | 42 | 73 | 38 | 0.203 |
| Ronald Belisario | 70.2 | 4 | 3 | 2.04 | 0 | 7 | 64 | 29 | 0.201 |
| Clayton Kershaw | 171.0 | 8 | 8 | 2.79 | 0 | 0 | 185 | 91 | 0.200 |
| Sean Burnett | 32.1 | 1 | 2 | 3.06 | 1 | 2 | 23 | 15 | 0.200 |
| Dan Wheeler | 57.2 | 4 | 5 | 3.28 | 2 | 6 | 45 | 9 | 0.199 |
| David Weathers | 38.0 | 3 | 3 | 3.32 | 1 | 4 | 27 | 17 | 0.199 |
| Josh Fogg | 45.2 | 0 | 2 | 3.74 | 0 | 0 | 27 | 20 | 0.198 |
| Hong-Chih Kuo | 30.0 | 2 | 0 | 3.00 | 0 | 1 | 32 | 13 | 0.198 |
| Arthur Rhodes | 53.1 | 1 | 1 | 2.53 | 0 | 2 | 48 | 20 | 0.198 |
| Trever Miller | 43.2 | 4 | 1 | 2.06 | 0 | 1 | 46 | 11 | 0.197 |
| Jeremy Affeldt | 62.1 | 2 | 2 | 1.73 | 0 | 0 | 55 | 31 | 0.197 |
| Mariano Rivera | 66.1 | 3 | 3 | 1.76 | 44 | 46 | 72 | 12 | 0.197 |
| J.P. Howell | 66.2 | 7 | 5 | 2.84 | 17 | 25 | 79 | 33 | 0.197 |
| Chris Pérez | 23.2 | 1 | 1 | 4.18 | 1 | 2 | 30 | 15 | 0.195 |
| Huston Street | 61.2 | 4 | 1 | 3.06 | 35 | 37 | 70 | 13 | 0.194 |
| Rafael Soriano | 75.2 | 1 | 6 | 2.97 | 27 | 31 | 102 | 27 | 0.194 |
| Tony Sipp | 40.0 | 2 | 0 | 2.93 | 0 | 0 | 48 | 25 | 0.194 |
| George Sherrill | 27.2 | 1 | 0 | 0.65 | 1 | 3 | 22 | 11 | 0.192 |
| Ángel Guzmán | 61.0 | 3 | 3 | 2.95 | 1 | 1 | 47 | 23 | 0.192 |
| Edinson Vólquez | 49.2 | 4 | 2 | 4.35 | 0 | 0 | 47 | 32 | 0.191 |
| Craig Breslow | 55.1 | 7 | 5 | 2.60 | 0 | 2 | 44 | 18 | 0.191 |
| Juan Rincón | 26.1 | 3 | 2 | 7.52 | 0 | 0 | 25 | 20 | 0.191 |
| David Aardsma | 71.1 | 3 | 6 | 2.52 | 38 | 42 | 80 | 34 | 0.190 |
| Rafael Betancourt | 25.1 | 3 | 1 | 1.78 | 1 | 3 | 29 | 5 | 0.189 |
| Michael Wuertz | 78.2 | 6 | 1 | 2.63 | 4 | 6 | 102 | 23 | 0.188 |
| Darren O'Day | 55.2 | 2 | 1 | 1.94 | 2 | 2 | 54 | 17 | 0.188 |
| Fu-Te Ni | 31.0 | 0 | 0 | 2.61 | 0 | 2 | 21 | 11 | 0.187 |
| Trevor Hoffman | 54.0 | 3 | 2 | 1.83 | 37 | 41 | 48 | 14 | 0.183 |
| Kiko Calero | 60.0 | 2 | 2 | 1.95 | 0 | 5 | 69 | 30 | 0.180 |
| Tim Byrdak | 61.1 | 1 | 2 | 3.23 | 0 | 2 | 58 | 36 | 0.178 |
| Claudio Vargas | 30.1 | 1 | 0 | 1.78 | 0 | 2 | 20 | 11 | 0.175 |
| Tyler Clippard | 60.1 | 4 | 2 | 2.69 | 0 | 1 | 67 | 32 | 0.172 |
| Joe Nathan | 68.2 | 2 | 2 | 2.10 | 47 | 52 | 89 | 22 | 0.171 |
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